Researchers report on sublingual immunotherapy for NR protein allergies

ERJ staff report (DS)

Madrid -- Researchers at the Department of Allergology at Hospital Santiago-Apostol in Vitoria-Gasteiz, Spain have carried out a randomised, double-blind, placebo-controlled clinical trial on patients suffering from allergies to proteins found in natural rubber latex. The aim of the study was to assess the efficacy and tolerability of latex sublingual immunotherapy in adult patients who have to avoid all latex materials.

Twenty-eight adult latex-allergic patients (five males and 23 females), with an average age of 39 years (range 24-57) were randomised to receive a commercial latex-sublingual immunotherapy or placebo during one year, followed by another year of open, active therapy.

The researchers say that further studies are needed to evaluate latex-sublingual immunotherapy, since efficacy could not be demonstrated in adult patients with avoidance of the allergen.

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Abstract of paper from Infection Control Today